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Hillsborough, NC

Developing fungi-derived products for pharmaceuticals and agriculture.

• Fungal Biotechnology: Clue Genetics uses fungi to develop solutions for pharmaceuticals, agriculture, and pollution mitigation.
• Expert Team: The team includes experts in mycology, genomics, and medicinal chemistry with decades of experience.
• Proprietary Library: Clue Genetics owns a fungal strain library of over 50,000 living isolates, with multiple strains licensed.
• Antifungal Focus: The company is advancing candidates for antifungal treatments, targeting Candida auris.
• Licensing Model: The business model centers on licensing compounds to high-value industries.

Clue Genetics is an early-stage biotech company leveraging the potential of fungi to develop natural products for various industries. The company utilizes chemical and genomic analysis to identify fungi-derived biological molecules with applications in pharmaceuticals, agriculture, food, cosmetics, and industrial biotechnology. Clue Genetics has developed intellectual property around these active molecules and aims to capture value through its own products and licenses to partners. The company’s library of approximately 50,000 fungal strains, spanning six continents, serves as the foundation for its technology platform, offering nature-based solutions to global challenges.

Clue Genetics is raising funds to advance early candidates towards pre-clinical development, focusing initially on antifungal products targeting the emergent human pathogen, Candida auris. This pathogen poses a significant threat due to its multidrug resistance and rapid global spread. Clue Genetics has identified fungal strains effective against Candida species and plans to expand its operations by developing additional intellectual property and advancing its leads for Candida treatments and crop protection. The company’s business model includes licensing to industry partners and developing private label products in sectors with lower barriers to entry, such as biologically based crop protection.

Company Info

Clue Genetics develops fungi-derived natural products for pharmaceuticals, agriculture, and industrial applications using a vast strain library.

Clue Genetics is a biotechnology company focused on harnessing the potential of fungi to develop natural products for various industries. Utilizing a proprietary library of over 50,000 fungal strains, the company employs chemical and genomic analysis to identify bioactive molecules with applications in pharmaceuticals, agriculture, and industrial biotechnology. Clue Genetics aims to generate value through licensing agreements and the development of its own products, addressing global challenges such as disease treatment and sustainable agriculture.

The company’s approach involves sequencing, screening, and synthetic biology to explore the vast biosynthetic potential of fungi. With a team of experts in mycology, genomics, and medicinal chemistry, Clue Genetics is positioned to license its discoveries to high-value sectors. The company has already genotyped over 3,000 strains and secured initial licensing revenues, laying the groundwork for further development and commercialization of its fungal-derived solutions.